Methanospirillum
hungatei cells and
flagella structure
(Gunsalus Lab)

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Heatmap representing gene expression for 11,306 differentially expressed genes over the diurnal cycle.

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Atomic structures
of low-complexity
protein segments
reveal kinked β sheets
that assemble networks
(Eisenberg Lab)

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The UCLA-DOE Institute is a team of research laboratories working on fundamental research and technology developments in broad DOE mission areas ranging from microbes, to biofuels and green chemistry, to the design of new biomaterials.

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Sabeeha Merchant, Siobhan Braybrook, Matteo Pellegrini, Keriann Backus

Using state of the art methodologies for genome-wide approaches to probe the enzymology, cell biology and metabolism of organisms that contribute to carbon capture and primary productivity

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Robert Gunsalus, Robert Clubb, Joseph Loo, Matteo Pellegrini

Deciphering the metabolism of syntrophic microbial communities and the biogenesis of the cellulosome appendage of the model cellulose degrading microbe, Clostridium thermocellum

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James Bowie, Robert Clubb, Todd Yeates

Developing new technologies to carry out important biosynthetic and biodegradation reaction schemes in vitro through the design of novel pathways and enzyme systems

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Jose Rodriguez, David Eisenberg, Todd Yeates

Pioneering the new method of micro-electron diffraction (microED); revealing microscale substructure within protein crystals at unprecedented levels of detail

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The Institute mentors and provides learning resources for students from around the world

Notable Awards and Papers by Investigators

345 403 DOE-MBI Staff 2020-02-20 12:14:06The Cell Wall - iBiology - by Siobhan Braybrook
The archaeal motility structure (flagellum /archaellum) During…
A day in the life of Chlamydomonas The unicellular green alga…
181 220 DOE-MBI Staff 2018-09-17 15:01:56Development of a new enzyme reagent that labels proteins with peptides via a specific lysine-isopeptide bond at high yield (Clubb lab)
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